Pamela Isely was botanist working underneath professor Jason Woodrue until an accident gave her powers and turned her insane. Taking the name Poison Ivy she became a super-villain and eco-terrorist with the ability to control plants, which brought her into conflict with Gotham's superheroes, especially Batman. Poison Ivy's desire is the protection of the sanctity and supremacy of nature at all costs, she sadistically lashes out against humanity which she sees as a blight upon the planet. Frequently Poison Ivy teams up with her best friend and partner in crime, Harley Quinn. Although much of her life has been spent imprisoned in Arkham Asylum for the criminally insane, she has also held down a S.T.A.R. Labs position. She has been a member of the Gotham City Sirens, the Injustice League, Injustice Gang, the Secret Society of Super-Villains and the Suicide Squad.